The Colts are two games up on the Vikings and Rams for the #1 overall pick.
Currently if all three teams finished with two losses, the strength of schedule tiebreaker looks like this:
Colts: 95-81 (.540)
Vikings: 102-74 (.580)
Rams: 103-76 (.575)
So the Colts have a healthy leg up.
Here's who to root for:
Broncos at Vikings
Rams at 49ers
Obviously, if the Vikes or Rams win, it's go fly for Indy.
Chargers at Jaguars
Falcons at Texans
Titans at Bills
It's easy to root against the AFC South.
Jets at Redskins
Rams and Vikes both play Washington
Chiefs at Bears
Lions at Saints
Indy played KC but not Chicago, same with NO and Det.
Packers at Giants
Vikes play Green Bay twice.
Panthers at Bucs
Carolina is all but out of it, but they are at 3 wins, so pull for them anyway.
Raiders at Dolphins
Vikes play the Raiders. Dolphins only have 3 wins. Let's worry about the Vikes.